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Total 42604 results found since Jan 2013.

Bio-absorbable antibiotic impregnated beads for the treatment of prosthetic vascular graft infections.
CONCLUSION: This report details the successful use of bio-absorbable antibiotic beads for the treatment prosthetic vascular graft infections in patients at high risk for graft explant or major vascular reconstruction. At early follow-up, we demonstrate successful infection suppression, graft preservation, and limb salvage with the use of these beads in a subset of vascular patients. PMID: 26896286 [PubMed - as supplied by publisher]
Source: Vascular - February 18, 2016 Category: Surgery Authors: Genovese EA, Avgerinos ED, Baril DT, Makaroun MS, Chaer RA Tags: Vascular Source Type: research

AGEs accumulation is related to muscle degeneration and vascular calcification in peritoneal dialysis patients
CONCLUSIONS: The study revealed associations between AGEs accumulation and lower muscle stiffness/density. Associations that linked muscle degeneration parameters with vascular calcification were observed.PMID:33650629 | DOI:10.1590/2175-8239-JBN-2020-0119
Source: Jornal Brasileiro de Nefrologia - March 2, 2021 Category: Urology & Nephrology Authors: La ís de Faria Fonseca Anna Beatriz Ara újo K élcia Rosana da Silva Quadros Cinthia Esbrile Moraes Carbonara S érgio San Juan Dertkigil Andrei Carvalho Sposito Rodrigo Bueno de Oliveira Source Type: research

Preliminary comparisons between in vivo ultrasonographic virtual histology and histopathological findings of endarterectomized carotid plaque
CONCLUSION: This study confirmed the usefulness of noninvasive USVH. Further technical improvements and software developments may promote the clinical application of this method.
Source: Jornal Vascular Brasileiro - December 7, 2013 Category: Surgery Source Type: research

Role of NMDA receptors in vascular remodelling associated to pulmonary hypertension
ConclusionGlutamatergic signaling through pulmonary vascular NMDAR occurs in PAH pathophysiology and may represent a new therapeutic target.Support: INSERM, Univ. Paris-Sud, CCML, LabEx LERMIT, FRSR.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Dumas, S. J., Perros, F., Bru-Mercier, G., Ranchoux, B., Rucker-Martin, C., Gouadon, E., Vocelle, M., Dorfmuller, P., Fadel, E., Humbert, M., Cohen-Kaminsky, S. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

LSC Abstract - Glutamatergic signaling through pulmonary vascular NMDA receptors in pulmonary hypertension
Conclusion: Glutamatergic signaling through pulmonary vascular NMDAR occurs in PAH pathophysiology and may represent a new therapeutic target.
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Dumas, S. J., Perros, F., Bru-Mercier, G., Courboulin, A., Ranchoux, B., Rücker-Martin, C., Gouadon, E., Vocelle, M., Raymond, N., Dorfmüller, P., Fadel, E., Humbert, M., Cohen-Kaminsky, S. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

PLC (Phospholipase C) β2 Promotes VEGF (Vascular Endothelial Growth Factor)-Induced Vascular Permeability
CONCLUSIONS: The results implicate PLCβ2 as a key positive regulator of VEGF-induced vascular permeability through regulation of both calcium flux and phosphatidylinositol 4,5-bisphosphate levels at the cellular level. Targeting of PLCβ2 in a therapeutic setting may provide a novel approach to regulating vascular permeability in patients.PMID:35861069 | DOI:10.1161/ATVBAHA.122.317645
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 21, 2022 Category: Cardiology Authors: Kathryn N Phoenix Zhichao Yue Lixia Yue Chunxia G Cronin Bruce T Liang Luke H Hoeppner Kevin P Claffey Source Type: research

Calciprotein Particles: Balancing Mineral Homeostasis and Vascular Pathology
Arterioscler Thromb Vasc Biol. 2021 Mar 11:ATVBAHA120315697. doi: 10.1161/ATVBAHA.120.315697. Online ahead of print.ABSTRACTHypercalcemia and hyperphosphatemia associate with an elevated risk of cardiovascular events, yet the pathophysiological basis of this association is unclear. Disturbed mineral homeostasis and the associated hypercalcemia and hyperphosphatemia may result in the formation of circulating calciprotein particles (CPPs) that aggregate the excessive calcium and phosphate ions. If not counteracted, the initially formed harmless amorphous spherical complexes (primary CPPs) may mature into damaging crystalline...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 11, 2021 Category: Cardiology Authors: Anton G Kutikhin Lian Feenstra Alexander E Kostyunin Arseniy E Yuzhalin Jan-Luuk Hillebrands Guido Krenning Source Type: research